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Do Women Really Need a Female-Targeted Viagra?
Do Women Really Need a Female-Targeted Viagra?
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Article Author : dwells (261 days ago)

Viagra is one of the most successful and life-changing drugs to ever have been invented, and has caused a stir in the sex industry ever since it was created – it is now used by over 20 million men worldwide for the treatment of erectile dysfunction. However, a version for women has never been found, despite numerous researchers in a number of companies searching for an answer to this problem. Despite the search being on-going for more than a decade, no-one has ever found a problem to the female sex drive issue. The latest disappointment to add to the list is a drug known as flibanserin, which is a contender for the first approved drug to combat low sexual desire in women.

 

The Food and Drug Administration advisory panel advised against it’s approval, stating that the slight increase in female sexual satisfaction wasn’t enough to outweigh the potential side effects, such as fatigue and depression. Though it is more commonly publicised as a male problem, women do experience sexual dysfunction as well. However, experts claim that the problems is all too often a lack of desire rather than a physical problem with performing. There is a risk of GPs and medical professionals over-diagnosing women with a hypoactive sexual dysfunction, which is characterised by a low sexual desire, which can cause distress. However, for many women, this issue doesn’t need to be treated with a pill – it can be easily treated with therapy or other approaches. Taking a pill, they say, would be an easy way out. It’s true that some women could benefit from a drug to increase their sexual appetite, but they are unsure how many women this would include. Viagra is something of a one-size-fits-all treatment, whereas the same for women wouldn’t necessarily be the case.

 

Studies show that around one in ten women in the U.S experience some form of HSDD, but there is no such thing as a normal sex drive in order to determine how often a woman should be craving sex in order to be considered healthy. This is where the problem lies – a low sex drive can often be relative to the person suffering from it. There are also two other common sexual complaints in female patients, which are arousal and orgasmic disorder. Around five percent of women suffer with this problem and this can often affect other problems such as your sex drive. With this in mind, how can you tell what is affecting your sex drive?

 

The first step if you’re struggling with a low sex drive is to talk to your GP. Many women don’t discuss such problems with their doctor due to embarrassment or because they feel as though their GP isn’t interested in what they have to say. But other medical conditions may be involved, so discussing it is vital in order to get to the root of the issue. It is advised that you book a separate appointment to discuss the problem, rather than trying to fit it into an appointment about another health concern, as it requires a lot of questions and possibly a physical exam. If you’re more interested in sex when you’re not tired, such as when you’re on holiday, then it may be easy to decipher that the problem is fatigue. Your GP may suggest making some lifestyle changes to see if this solves the issue. However, hormonal changes as you age may also be a cause, so it’s vital that you explain everything to your GP so that they can help you.

Allergies And Asthma

Could Colds During Pregnancy Lead To Child As...
Studies suggest that mothers who catch a cold during pregnancy could be more likely to have children who develop asthma, as the bacteria and viruses affect the in-utero environment. Babies who are exposed to the allergens are more likely to become sensitive to them and this could affect them later in life, according to researchers. The new study, which examined the risk of the common cold to unborn children, shows that women who are pregnant should take extra precautions around people who have colds and are sneezing, as it could lead to problems for their children later in life. The mothers infections and bacterial exposure during the pregnancy leads to the environment in the womb being altered. Allergist Dr Mitch Grayson stated that in addition to this, the same children in the study who had early exposure to allergens, including house dust and pet hair, also had increased odds of becoming sensitive by the age of five. When dust mites from the mother and the child’s mattresses were analysed, children with high dust mite exposure yet low bacteria exposure were more likely to develop allergies to dust mites than those with low dust mite exposure and high bacteria exposure.   Researchers looked at 513 pregnant women in Germany, and their 526 children. The women completed questionnaires during the pregnancy, when the children were 3 and 12 months old, and then every year up until the children reached five years old. Of the families, 61 per cent of them had a parent with asthma, hay fever or atopic dermatitis. According to the ACAAI, asthma and allergies can be hereditary; if both parents have allergies, the child is as much as 75 per cent more likely to be allergic. If just one parent is allergic, or if a close relative has allergies, then the child has a 30 to 40 per cent chance of developing some form of allergy. This drops to just 10 to 15 per cent if neither parent has an allergy. Researchers claim that they now know for certain that allergies and asthma can develop in the womb, as genetics play an important factor in both diseases. However, this study sheds light on how the environment a mother creates during pregnancy can begin to affect the child before it’s even been born. Asthma is the most common potentially serious medical condition to complicate pregnancy, according to the ACAAI.   Asthma affects around 1 in 12 women during their childbearing years, and when women with asthma become pregnant, one third of the patients improve, one third get worse, and one third remain unchanged. Asthma is a serious condition which affects a number of people and has numerous triggers, including house mites, dust, pollen and pollution. As pollution and toxins in the air have increased over the years, the risk of developing respiratory diseases has also increased. There are ways to treat asthma and, depending on the severity of the condition, your child may require medication to maintain it. If you're concerned about the risk colds and asthma have to your baby, or think your child is developing symptoms of asthma, you should seek advice from your GP as soon as possible. As with any pregnancy, it's important to stay as healthy as possible, maintain a balanced diet which includes all the nutrients both you and your baby need, and get enough exercise; you should also avoid alcohol and smoking, to maintain good health for both you and your baby.
Could Second-Hand Smoke Be Damaging Your Chil...
A new study has found that the health concerns associated with the wellness and wellbeing of children who live with smokers could be more serious than previously thought. A shocking report shows that children who are exposed to cigarette smoke at home do not respond as well to asthma treatment as those who live with non-smoking parents in a non-smoking household.   Children who are regularly exposed to cigarette smoke had lower levels of an enzyme that helps them to respond to the main asthma treatments. This report was published in a journal called Chest recently.   This is bad news, as the number of children in the UK who have asthma is on the increase. Over a million children in this country are believed to be suffering from asthma, and they are most commonly treated by steroids and inhalers. For some patients, however, these treatments are not totally effective, leaving them unprotected from harm in the event of an attack.   It is now known that passive smoke can not only worsen the symptoms of asthma in children, but can actually impair their response to treatments in the form of inhaled steroids. It is not yet known how or why this effect occurs.   Researchers into the subject have found that children who have severe asthma, and parents who smoke at home, have a lower level of an enzyme called HDAC2, especially when compared like for like with children who do not have smoking parents.   This enzyme – HDAC2 – is required in the human body to help it benefit from steroids, and to allow them to exert their anti-inflammatory type effects over the symptoms of asthma.   To come to this conclusion, researchers looked at a group of 19 children who were suffering from severe asthma. Nine of the children in the group had a parent who smoked whilst ten of the children had parents who were non smokers.

Cancer

TapImmune Appoints Leading Immunotherapy Rese...
Go to Source   TapImmune Inc. (OTCQB:TPIV) is pleased to announce that Dr. Keith Knutson, PhD (www.vgtifl.org/keith-knutson-phd) has been appointed to chair the company's scientific advisory board. Dr. Knutson is Director of the Cancer Vaccines and Immune Therapies Program at the Vaccine & Gene Therapy Institute of Florida, a nonprofit biomedical research institute in Port St. Lucie, FL (VGTI Florida). TapImmune has licensed cancer vaccine technologies originating from Dr. Knutson's former laboratory at the Mayo Clinic, which are currently completing Phase I clinical trials in breast and ovarian cancer. The start of Phase II clinical studies in planned for the end of 2014. Glynn Wilson, TapImmune CEO said, "We are delighted to have someone with Keith's vision and scientific knowledge to lead our scientific advisory board. As a recognized leader in immunotherapy of breast and ovarian cancer, it is a great to have his input into the Company's clinical development programs. Under Dr. Knutson's leadership, TapImmune will continue to build a world-class scientific advisory board to review and advance all scientific programs."
    "I have been impressed by the comprehensive approach to immunotherapy at TapImmune which looks at both T-cell stimulation and antigen presentation," said Dr. Knutson. "I look forward to leading this advisory board and recruiting additional scientific input that will serve to provide the best scientific approaches for the Company."     Before joining VGTI Florida, Dr. Knutson was the Director of the Mayo Clinic Cancer Center Immunology and Immunotherapy Program at the Mayo Clinic, Rochester, Minnesota. He retains adjunct faculty positions at the Mayo Clinic and Florida Atlantic University. Until recently, he was a standing member of the U.S. Department of Defense's Breast Cancer Research Program Integration Panel and is a current member of the Tumor Microenvironment Study Section at the National Institutes of Health. He was previously the Co-Director of the Mayo Clinic Immune Monitoring Core which engaged in providing a variety of different immune monitoring and phenotyping services for research purposes across a variety of scientific disciplines including tumor immunology, rheumatoid arthritis, and infectious diseases.     Dr. Knutson's current interests and research focuses on the immunology and immunotherapy of breast and ovarian cancers. Interests are in both the basic immunobiology and clinical translation, including clinical trials. His laboratory conducts research on cancer vaccines focusing on augmenting T cell immunity using peptide and virus-based vaccines. His research is also aimed at understanding how tumors evade the immune system and immune therapies as well as identifying immunologic biomarkers or proteins that could be useful in identifying breast cancer patients who are unlikely to respond to certain therapies. Dr. Knutson graduated from the University of Washington, Seattle at the top of his class in Microbiology and earned his Ph.D. in Pharmacology and Physiology from the University of Georgia. Following postdoctoral training, Dr. Knutson was awarded the Howard Temin Award from the National Cancer Institute and he has published over 120 articles in prestigious journals such as Nature Medicine, Cancer Research, and the Journal of Clinical Oncology. His laboratory is funded by several grants from the Department of Defense, The National Cancer Institute, The Susan G. Komen for the Cure Foundation, and various other foundations.     About TapImmune Inc. TapImmune Inc. is an immunotherapy company specializing in the development of innovative vaccine technologies for the treatment of cancer and infectious disease. The Company's vaccine compositions, peptide or nucleic acid-based, comprise one or multiple naturally processed epitopes (NPEs) designed to comprehensively stimulate a patients' killer T-cells, helper T-cells and to restore or further augment antigen presentation by the modulation of TAP (Transporter associated with Antigen Processing). The Company believes that its vaccine compositions may be used as stand-alone medications or in combination with current treatment modalities. Please visit the Company's website at www.tapimmune.com for details.     Forward-Looking Statement Disclaimer: This release contains forward-looking information within the meaning of the Private Securities Litigation Reform Act of 1995. Statements in this news release concerning the Company's expectations, plans, business outlook or future performance, and any other statements concerning assumptions made or expectations as to any future events, conditions, performance or other matters, are "forward-looking statements". Forward-looking statements are by their nature subject to risks, uncertainties and other factors which could cause actual results to differ materially from those stored in such statements. Such risks, uncertainties and factors include, but are not limited to the risks set forth in the Company's most recent Form 10-K and other SEC filings which are available through EDGAR at www.sec.gov. The Company assumes no obligation to update the forward-looking statements
Scottsdale Healthcare clinical trial shows pr...
Go to Source   A clinical trial conducted by researchers at the Virginia G. Piper Cancer Center Clinical Trials showed that a new drug called MM-398 has produced a significant overall survival rate in patients with advanced, previously-treated pancreatic cancer.   The clinical trials are possible through a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute, according to a press release.   The NAPOLI-1 Phase 3 study -- a final confirmation of a drug’s safety and effectiveness -- was conducted among patients with metastatic pancreatic cancer who previously received gemcitibine, which has been the standard-of-care therapy for such patients, the release states.   The study, sponsored by Merrimack Pharmaceuticals, evaluated 417 patients enrolled at more than 100 sites in North America, South America, Europe, Asia and Australia.   Merrimack expects to submit a New Drug Application this year to the U.S. Food and Drug Administration (FDA) for the MM-398 combination regimen, the release states.   “This demonstration of a survival benefit from the MM-398 plus 5-FU and leucovorin combination is particularly important given that we have very few treatment options for patients in this tough clinical setting,” said Dr. Daniel D. Von Hoff, global principal investigator of the NAPOLI-1 study.   “The results of the NAPOLI-1 study are important because of the critical need to help patients with this devastating illness and move forward towards FDA approval.”   Each year in the U.S., nearly 46,000 people are diagnosed with pancreatic cancer, and more than 39,000 patients die, making it the fourth leading cause of cancer death, according to the release.   Only about 1 in 4 patients survive more than one year after diagnosis, and only 6 percent survivor more than five years.   This study will be presented at the European Society for Medical Oncology World Conference on Gastrointestinal Cancer being held June 25-28 in Barcelona, Spain, the release states.

Diabetes

Can Yoghurt Be Connected To Lower Diabetes Ri...
The media is always claiming that certain ingredients can help us to maintain a healthy lifestyle and improve our wellbeing. The latest headlines state that yoghurt is key to beating diabetes; a claim based on a study which associates dairy with the risk of developing type 2 diabetes. The study found that the risk of diabetes was significantly lowered by as much as 28 per cent in people who ate large amounts of low-fat yoghurt, compared to people who ate none at all. The results were similar in people who ate more of all low-fat fermented products, including cottage cheese and fromage frais. The study was based on people using food diaries to report their dairy intake around the time of eating, which is one of the best ways to gauge the success of a trial rather than asking people to recall what they’ve eaten throughout the day - it tends to be more accurate. The diaries were only used over a seven-day period (which isn’t a long enough to provide an accurate assessment of whether yoghurt can help with diabetes risks). It’s not currently clear whether fermented low-fat dairy products can help to prevent diabetes, but it is a theory researchers are keen to investigate. There are a number of steps you can take to lower your risk of developing diabetes though, such as regular exercise, eating a balanced healthy diet, quitting smoking and lowering your alcohol intake. It’s also important to note the sugar levels in the foods you eat, as these can contribute towards developing not just diabetes but also obesity. If you're concerned about your diet or weight, it's important to seek advice as this can contribute to a number of health concerns, in addition to diabetes, such as heart problems and certain cancers.   The study was carried out by the University of Cambridge, as part of a larger study funded by the Medical Research Council and Cancer Research UK. Researchers discovered that people who ate the most low-fat fermented products were 24 per cent less likely to develop type 2 diabetes than those who ate the least. The total dairy, high fat dairy, milk and cheese were not associated to the development of diabetes, nor was low-fat dairy. There are several limitations to this study which have led researchers to question whether or not yoghurt can actually help lower the risk of diabetes. Firstly, people’s reported dairy intake was only collected once, at baseline, over a seven-day period, so it’s possible that people’s diets didn’t stay the same during the 11 year follow-up period. Furthermore, the information was self-reported which could affect the reliability. Lastly, researchers didn’t take into account the dairy products included in cooking composite dishes. While there were attempts to take account of other factors, it is always possible that measured and unmeasured factors had an influence on the results. Further studies need to take place in order to know for certain whether fermented products can help to lower the risk of diabetes. The results do suggest that switching sugary snacks and meals for low-fat dairy products could help your overall health, as well as improving your diabetes prospects. Just be sure to choose low sugar varieties and to balance your diet with plenty of fruit and vegetables, grains and lean protein to ensure your body is getting all the nutrients it needs to stay healthy.
The Foot Problems Associated With Diabetes...
Diabetes is a well-known health concern. It’s growing too – type 2 diabetes is one of the fastest growing conditions in the western world, and that’s thought to be due to increasingly bad diets that people have. The increased levels of fat and sugar are very bad for our blood and diabetes is the end result of this. Diabetes famously causes a number of serious health problems and many people worry a lot about it. It is common knowledge that diabetes puts you at risk of having other serious problems, but you may not know that it can be a real burden for your feet. Here is a breakdown of why diabetes can be bad for your feet.   One of the major problems with your feet when you have diabetes is called diabetic neuropathy. What happens when you have this is that you’ll begin to feel a lack of sensation in your feet and your legs. This is often accompanied by a tingling or burning sensation as well as pain and completely numbness in the affected area. The cause of this problem is actually nerve damage that has come about due to the effects of uncontrolled diabetes. The problem is that it leads to a whole range of other issues with your feet such as the inability to move it properly and this can clearly lead to problems walking or doing anything that involves your feet.   There is also another serious condition of the feet that manifests itself due to diabetes. It is called peripheral vascular disease, and it causes poor blood flow that affects the ability of sores or cuts on your feet to heal themselves. Your feet are actually very prone to this kind of problem due to the general wear and tear that daily life places upon them – and unfortunately the lack of ability to heal puts you at very serious risk of gangrene and ulcers.   Apart from these very serious issues with your feet, it’s true that diabetes can be a tertiary cause of other problems with your feet. While these will not be a very dangerous problem on their own, with the threats of diabetes that can develop, these less serious issues become something that could potentially cause you to require surgery or even amputation.   One major issue that you may not think to worry about is athlete’s foot. Athlete’s foot is a fungal infection that can cause itchiness and the break of skin, as we have already seen that diabetic neuropathy is a huge problem with regards to broken skin, it’s easy to see how athlete’s foot can become a very problematic condition.   Aside from conditions like athlete’s foot there are many other smaller problems that we usually wouldn’t worry about that can be a serious issue if you have diabetes and the foot conditions associated with it. Even things as seemingly meaningless as corns, hard skin, dry skin, bunions and blisters can develop into quite horrible concerns for your health.   So how can you avoid these problems and retain a healthy and happy lifestyle despite your diabetes? The first point is that you should always remember to take care of your healthy generally and stay in control of your diabetes. Problems associated with diabetes can only become a concern when you neglect your health. It’s also important that you take care of your feet and check them every day for any potential problems. If you find any then it is essential that you visit your doctor as soon as possible so that you can be prescribed a treatment that will be effective.